| Identification | Back Directory | [Name]
LpxH-IN-2 | [CAS]
2923230-41-3 | [Synonyms]
LpxH-IN-2
Cyclohexanecarboxamide, 4-[[2-[4-[[4-[(4R)-4-amino-2-oxo-1-pyrrolidinyl]phenyl]sulfonyl]-1-piperazinyl]-6-chloro-4-pyridinyl]difluoromethyl]-, trans- | [Molecular Formula]
C27H33ClF2N6O4S | [MOL File]
2923230-41-3.mol | [Molecular Weight]
611.11 |
| Chemical Properties | Back Directory | [Boiling point ]
895.509±75.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.424±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
16.639±0.40(predicted) |
| Hazard Information | Back Directory | [Uses]
LpxH-IN-2 (compound 014) is a potent LpxH inhibitor. LpxH-IN-2 shows antibacterial activity for E. coli[1]. | [References]
[1] Benediktsdottir A, et al. Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors. Eur J Med Chem. 2024 Aug 22;278:116790. DOI:10.1016/j.ejmech.2024.116790 |
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