| Identification | Back Directory | [Name]
1H-Pyrazolo[3,4-d]pyrimidine-4,6-diamine, N6-[(2,4-difluorophenyl)methyl]-N4-(5-methyl-1H-pyrazol-3-yl)-1-(4-piperidinyl)- | [CAS]
2923999-01-1 | [Synonyms]
1H-Pyrazolo[3,4-d]pyrimidine-4,6-diamine, N6-[(2,4-difluorophenyl)methyl]-N4-(5-methyl-1H-pyrazol-3-yl)-1-(4-piperidinyl)- | [Molecular Formula]
C21H23F2N9 | [MOL File]
2923999-01-1.mol | [Molecular Weight]
439.47 |
| Chemical Properties | Back Directory | [Boiling point ]
722.1±70.0 °C(predicted) | [density ]
1.56±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
14.10±0.10(predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Uses]
PLK4-IN-4 (compound 22) is a potent PLK4 inhibitor with an IC50 value of 7.9 nM. PLK4-IN-4 has the potential for the research of cancer[1]. | [IC 50]
PLK4: 7.9 nM (IC50) | [References]
[1] DongMei Zhao, et al. Pyrazolopyrimidine derivative, and preparation method and application thereof. CN116023380A. |
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