| Identification | Back Directory | [Name]
Thalidomide-piperidine | [CAS]
2924858-38-6 | [Synonyms]
Thalidomide-piperidine
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(1-piperidinyl)- | [Molecular Formula]
C18H19N3O4 | [MOL File]
2924858-38-6.mol | [Molecular Weight]
341.36 |
| Chemical Properties | Back Directory | [Boiling point ]
600.3±50.0 °C(predicted) | [density ]
1.399±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
10.75±0.40(predicted) |
| Hazard Information | Back Directory | [Uses]
Thalidomide-piperidine is an E3 Ligase Ligand-Linker Conjugate. Thalidomide-piperidine can be used to synthesize SMART1 (HY-W998345)[1]. | [References]
[1] Peng Z, et al. Targeting Smurf1 to block PDK1-Akt signaling in KRAS-mutated colorectal cancer. Nat Chem Biol. 2024 Jul 22. DOI:10.1038/s41589-024-01683-5 |
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