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CDK2-IN-27 (compound 1) is a potent CDK2 inhibitor with IC50 values of <10, >10-20 nM for CDK2/cyclin E1, CDK2/cyclin B1, respectively[1]. | [IC 50]
CDK2/cyclin E1: <10 nM (IC50); CDK1/cyclinB1: >10-20 nM nM (IC50) | [References]
[1] Richard Vargas, et al. Cdk2 inhibitors and methods of making and using same. WO2023092088A1. |
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