| Identification | Back Directory | [Name]
3-Cyclobutene-1,2-dione, 3-[(4-aminophenyl)amino]-4-[[1-(phenylmethyl)-4-piperidinyl]amino]- | [CAS]
2937454-22-1 | [Synonyms]
3-Cyclobutene-1,2-dione, 3-[(4-aminophenyl)amino]-4-[[1-(phenylmethyl)-4-piperidinyl]amino]- | [Molecular Formula]
C22H24N4O2 | [MOL File]
2937454-22-1.mol | [Molecular Weight]
376.45 |
| Hazard Information | Back Directory | [Uses]
AChE-IN-30 is an AChE inhibitor with an IC50 value of 4.4 μM. AChE-IN-30 has neuroprotective activity, and inhibits H2O2-induced apoptosis by suppressing intracellular ROS accumulation. AChE-IN-30 can be used for research of Alzheimer's disease[1]. | [References]
[1] Wan D, et al. Design, Synthesis, and Biological Activity of Donepezil: Aromatic Amine Hybrids as Anti-Alzheimerss Drugs. ACS Omega. 2023 Jun 5;8(24):21802-21812. DOI:10.1021/acsomega.3c01427 |
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