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2944459-58-7

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2944459-58-7 Structure

2944459-58-7 Structure
IdentificationBack Directory
[Name]

HDAC-IN-60
[CAS]

2944459-58-7
[Synonyms]

HDAC-IN-60
Acetamide, N-hydroxy-2-[[2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]phenyl]amino]-
[Molecular Formula]

C20H26N2O6
[MOL File]

2944459-58-7.mol
[Molecular Weight]

390.43
Chemical PropertiesBack Directory
[density ]

1.226±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[pka]

9.642±0.20(predicted)
Hazard InformationBack Directory
[Uses]

HDAC-IN-60 (compound 21a) is a potent histone deacetylase (HDAC) inhibitor. HDAC-IN-60 can promote the intracellular generation of ROS, cause DNA damage, block the cell cycle at G2/M phase, and activate the mitochondria-related apoptotic pathway to induce cell apoptosis[1].
[References]

[1] Yang Y, et, al. Design, Synthesis, and Biological Evaluation of Histone Deacetylase Inhibitors Derived from Erianin and Its Derivatives. ChemMedChem. 2023 Jul 3;18(13):e202300108. DOI:10.1002/cmdc.202300108
2944459-58-7 suppliers list
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Telephone: 13816613772
Website: https://www.chemicalbook.com/ShowSupplierProductsList16976/0_EN.htm
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
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