| Chemical Properties | Back Directory | [Boiling point ]
787.413±60.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.701±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
4.199±1.00(predicted) |
| Hazard Information | Back Directory | [Uses]
α-Glucosidase-IN-28 (Compound 18) is a α-Glucosidase inhibitor (IC50: 0.62 μM, Ki: 3.93 μM). α-Glucosidase-IN-28 binds to α-glucosidase at the original binding site (OBS), and forms multiple hydrophobic interactions with nearby amino acids. α-Glucosidase-IN-28 can be used for research of diabetes and related diseases[1]. | [References]
[1] Phan TH, et al. Designing Potent 伪-Glucosidase Inhibitors: A Synthesis and QSAR Modeling Approach for Biscoumarin Derivatives. ACS Omega. 2023 Jul 11;8(29):26340-26350. DOI:10.1021/acsomega.3c02868 |
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