| Identification | Back Directory | [Name]
THIONAZIN | [CAS]
297-97-2 | [Synonyms]
Cynem
cl18133
en18133
ac18133
Nemafos
zinofos
Ac 18133
Nemaphos
En 18133
Zenophos
Cl 18133
Cynophos
acc18133
Zynophos
CYNEM(R)
ZINOPHOS
THIONAZIN
Acc 18133
ent25,580
Ent 25,580
nemafos10g
Nematocide
NAMAFOS(R)
Thionazine
ZINOPHOS(R)
nematocidegr
Nemafos 10 g
Nematocide gr
ZINOPHOS (TM)
Thionazin PESTANAL
thionazin (bsi,iso)
rcrawastenumberp040
Thionazin solution
zinophos10-ggranular
ZINOPHOS, 100MG, NEAT
americancyanamid18133
Rcra waste number P040
American cyanamid 18133
Thionazin Solution, 100ppm
experimentalnematocide18,133
Experimental nematocide 18,133
Ethyl pyrazinyl phosphorothioate
zinophos4-eemulsifiableconcentrate
o,o-diethylo-pyrazinylthiophosphate
O,O-Diethyl O-pyrazinyl thiophosphate
diethylo-2-pyrazinylphosphorothionate
o,o-diethylo-pyrazinylphosphorothioate
Diethyl O-2-pyrazinyl phosphorothionate
O,O-DIETHYLO-2-PYRAZINYLPHOSPHOROTHIATE
O,O-DIETHYL-2-PYRAZINYL PHOSPHOROTHIOATE
o,o-diethylo-2-pyrazinylphosphorothionate
o,o-diethylo-pyrazin-2-ylphosphorothioate
o,o-Diethyl o-(2-pyrazinyl) thiophosphate
O,O-Diethyl O-2-pyrazinyl phosphothionate
O,O-Diaethyl-O-(2-pyrazinyl)-thionophosphat
THIONAZIN, 100 NG/ IN ACETONITRIL, PESTANAL
diethoxy-pyrazin-2-yloxy-thioxo-phosphorane
Thionazin: (Ethyl pyrazinyl phosphorothioate)
O,O-Diaethyl-O-(pyrazin-2yl)-monothiophosphat
O, O-DIETHYL O-(2-PYRAZINYL) PHOSPHOROTHIOATE
o,o-diaethyl-o-(pyrazin-2-yl)-monothiophosphat
phosphorothioicacid,o,o-diethylo-pyrazinylester
pyrazinol,o-esterwitho,o-diethylphosphorothioate
Thionazin Solution in Acetone/Toluene, 1000μg/mL
phosphorothioicacid,o,o-diethylo-2-pyrazinylester
Phosphorothioic acid, O,O-diethyl O-pyrazinyl ester
Phosphorothioic acid, O,O-diethyl O-2-pyrazinyl ester
O,O-diethyl O-pyrazin-2-yl phosphorothioate thionazin
diethoxy-pyrazin-2-yloxy-sulfanylidene-$l^{5}-phosphane
Pyrazinol, O-ester with O,O-diethyl phosphorothioic acid
O, O-Diethyl O-(2-pyrazinyl) phosphorothioate, Thionazin | [EINECS(EC#)]
206-049-6 | [Molecular Formula]
C8H13N2O3PS | [MDL Number]
MFCD00055349 | [MOL File]
297-97-2.mol | [Molecular Weight]
248.24 |
| Chemical Properties | Back Directory | [Melting point ]
-1.7℃ | [Boiling point ]
bp 80° | [density ]
1.204-1.210 g/cm3 (25 ºC) | [refractive index ]
1.5131 (589.3 nm 25℃) | [Fp ]
100 °C | [storage temp. ]
2-8°C | [solubility ]
Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
liquid | [pka]
-1.22±0.10(Predicted) | [Water Solubility ]
1.14g/L(25 ºC) | [BRN ]
884916 | [Henry's Law Constant]
1.0×101 mol/(m3Pa) at 25℃, Mackay et al. (2006) | [Stability:]
Hygroscopic | [Major Application]
agriculture
environmental | [InChI]
1S/C8H13N2O3PS/c1-3-11-14(15,12-4-2)13-8-7-9-5-6-10-8/h5-7H,3-4H2,1-2H3 | [InChIKey]
IRVDMKJLOCGUBJ-UHFFFAOYSA-N | [SMILES]
CCOP(=S)(OCC)Oc1cnccn1 | [EPA Substance Registry System]
Thionazin (297-97-2) |
| Hazard Information | Back Directory | [Chemical Properties]
Amber liquid. Slightly soluble in water; miscible with
most organic solvents. | [Uses]
Nematocide; insecticide. | [General Description]
Amber liquid. Pure compound is almost colorless; technical product is light brown to tan. Used in insecticides, fungicides, and nematocides. Not registered as a pesticide in the U.S. | [Reactivity Profile]
Organothiophosphates, such as THIONAZIN, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. | [Hazard]
Toxic by ingestion, inhalation, and skin
absorption; cholinesterase inhibitor. | [Health Hazard]
Cholinesterase inhibitor. (Non-Specific -- Organic Phosphate Compound, Liquid, Poison B). Poisonous; may be fatal if inhaled, swallowed or absorbed through skin. Contact may cause burns to skin and eyes. | [Fire Hazard]
(Non-Specific -- Organic Phosphate Compound, Liquid, Poison B). THIONAZIN may burn but does not ignite readily. (Non-Specific -- Organic Phosphate Compound, Liquid, Poison B). Fire may produce irritating or poisonous gases. | [Definition]
ChEBI: Thionazin is an organic thiophosphate. | [Production Methods]
Thionazin is commercially synthesised by esterifying pyrazin-2-ol with O,O-diethyl phosphorothioic acid chloride. The production process begins with the preparation of pyrazin-2-ol, which is reacted with O,O-diethyl phosphorothioic acid chloride under controlled conditions to form the active ester: O,O-diethyl O-(pyrazin-2-yl) phosphorothioate. This reaction typically occurs in an organic solvent like toluene or chloroform, using a base such as pyridine to neutralise the hydrochloric acid by-product. | [Mechanism of action]
Acetylcholinesterase (AchE) inhibitor. | [Pesticide Type]
Nematicide; Insecticide |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS06 | [Signal word ]
Danger | [Hazard statements ]
H300+H310 | [Precautionary statements ]
P262-P264-P270-P280-P301+P310-P302+P352+P310 | [Hazard Codes ]
T+,Xn,F | [Risk Statements ]
27/28-40-21/22-36-20/21/22-11 | [Safety Statements ]
36/37/39-38-45-36/37-26-16 | [RIDADR ]
3018 | [WGK Germany ]
2 | [RTECS ]
TF5775000 | [TSCA ]
TSCA listed | [HazardClass ]
6.1(a) | [PackingGroup ]
I | [HS Code ]
29339900 | [Storage Class]
6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | [Hazard Classifications]
Acute Tox. 1 Dermal
Acute Tox. 2 Oral | [Safety Profile]
Poison by ingestion,
skin contact, and ocular routes. A
cholinesterase inhibitor type of insecticide.
When heated to decomposition it emits highly toxic fumes of NOx, POx, and SOx.
See also PARATHION. | [Hazardous Substances Data]
297-97-2(Hazardous Substances Data) | [Toxicity]
LD50 in female, male rats (mg/kg): 3.5, 6.4 orally; 11, 17 dermally (Gaines) |
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