| Identification | Back Directory | [Name]
6-Bromo-3,4-dihydro-4-(3,4,5-trimethoxyphenyl)-benzo[h]quinolin-2(1H)-one | [CAS]
297157-87-0 | [Synonyms]
6-B345TTQ
6-B345TTQ >98% (HPLC)
6-Bromo-3,4-dihydro-4-(3,4,5-trimethoxyphenyl)-benzo[h]quinolin-2(1H)-one
Benzo[h]quinolin-2(1H)-one, 6-bromo-3,4-dihydro-4-(3,4,5-trimethoxyphenyl)- | [Molecular Formula]
C22H20BrNO4 | [MDL Number]
MFCD01988835 | [MOL File]
297157-87-0.mol | [Molecular Weight]
442.3 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
DMSO: ≥20mg/mL | [form ]
powder | [color ]
white to off-white | [InChI]
1S/C22H20BrNO4/c1-26-18-8-12(9-19(27-2)22(18)28-3)15-11-20(25)24-21-14-7-5-4-6-13(14)17(23)10-16(15)21/h4-10,15H,11H2,1-3H3,(H,24,25) | [InChIKey]
KPOXOTVERMGJQS-UHFFFAOYSA-N | [SMILES]
COc1cc(cc(OC)c1OC)C2CC(=O)Nc3c2cc(Br)c4ccccc34 |
| Safety Data | Back Directory | [Hazard Codes ]
N | [Risk Statements ]
50 | [Safety Statements ]
61 | [RIDADR ]
UN 3077 9 / PGIII | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Aquatic Acute 1
Aquatic Chronic 1 |
| Hazard Information | Back Directory | [Uses]
6-B345TTQ is an α4 integrin inhibitor that inhibits α4-Leupaxin interaction. 6-B345TTQ can be used in inflammation research[1]. | [Biological Activity]
6-B345TTQ is a non-cytotoxic inhibitor of α4 integrin paxillin interaction. | [References]
[1] Kummer C, et al. A small molecule that inhibits the interaction of paxillin and alpha 4 integrin inhibits accumulation of mononuclear leukocytes at a site of inflammation. J Biol Chem. 2010 Mar 26;285(13):9462-9469. DOI:10.1074/jbc.M109.066993 |
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Energy Chemical
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http://www.energy-chemical.com |
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TargetMol
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400-821-0310 15002144251 |
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www.targetmol.cn/ |
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