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2971837-95-1

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2971837-95-1 Structure

2971837-95-1 Structure
IdentificationBack Directory
[Name]

ERα degrader 8
[CAS]

2971837-95-1
[Synonyms]

ERα degrader 8
[Molecular Formula]

C27H21NO5
[MOL File]

2971837-95-1.mol
[Molecular Weight]

439.46
Chemical PropertiesBack Directory
[Boiling point ]

711.3±60.0 °C(predicted)
[density ]

1.322±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

8.09±0.40(predicted)
Hazard InformationBack Directory
[Uses]

ERα degrader 8 (Compound 18j) is a selective Estrogen Receptor degrader. ERα degrader 8 is degrader to MCF-7 cells with IC50 value of 0.15 μM[1].
[References]

[1] Lu Y, et al. Discovery of novel quinoline scaffold selective estrogen receptor degraders (SERDs) for treatment of ER positive breast cancer with enhanced antiproliferative bioactivity through immunogenic cell death (ICD) effects. European Journal of Medicinal Chemistry, 2024: 116534.
2971837-95-1 suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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