| Identification | Back Directory | [Name]
N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyridine-3-carboxamide | [CAS]
298207-49-5 | [Synonyms]
WAY-297342
FLT3-IN-16
N-(3-Carbamoyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)nicotinamide
N-[3-(aminocarbonyl)-4,5,6,7-tetrahydro-1-benzothien-2-yl]nicotinamide
N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyridine-3-carboxamide
3-Pyridinecarboxamide, N-[3-(aminocarbonyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]- | [Molecular Formula]
C15H15N3O2S | [MOL File]
298207-49-5.mol | [Molecular Weight]
301.36 |
| Chemical Properties | Back Directory | [Boiling point ]
394.8±42.0 °C(Predicted) | [density ]
1.391±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 25 mg/mL (82.96 mM; ultrasonic and warming and heat to 80°C) | [form ]
Solid | [pka]
11.73±0.20(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
FLT3-IN-16 is a potent FLT3 inhibitor with an IC50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia[1]. | [References]
[1] Patch RJ, et, al. Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3282-6. DOI:10.1016/j.bmcl.2006.03.032 |
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