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Antimalarial agent 37 (compound 33) is a selective inhibitor against Type Ⅱ kinase with antiplasmodial activity. Antimalarial agent 37 exhibited cytotoxicity and selectivity towards cancer cells HepG2 and MCF 7[1]. | [References]
[1] Wang L, et al., Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases. J Med Chem. 2024 Jan 12. doi: 10.1021/acs.jmedchem.3c02046 DOI:10.1021/acs.jmedchem.3c02046 |
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