ChemicalBook--->CAS DataBase List--->2982663-28-3

2982663-28-3

Request For Quotation

Directory

Chemical Properties

Hazard Information

2982663-28-3 Structure

2982663-28-3 Structure

Identification	Back Directory
[Name] NA
[CAS] 2982663-28-3
[Synonyms]
[Molecular Formula] C29H23ClN4O4
[MOL File] 2982663-28-3.mol
[Molecular Weight] 526.97

Chemical Properties	Back Directory
[Boiling point ] 878.8±65.0 °C(predicted)
[density ] 1.38±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 3.59±0.10(predicted)

Hazard Information	Back Directory
[Uses] GQN-B37-E is a potent selective binder and inhibitor of MCL-1. GQN-B37-E binds to the BH3-domain-binding pocket in MCL-1. GQN-B37-E exhibits binding affinity for MCL-1 at the submicromolar range (Ki = 0.6 μM) without apparent binding to BCL-2 or BCL-XL[1].
[IC 50] Mcl-1: 0.6 μM (Ki)
[References] [1] Gong Q, et al. Discovery of Phenylpyrazole Derivatives as a New Class of Selective Inhibitors of MCL-1 with Antitumor Activity. ACS Omega. 2024 Jun 13;9(25):27369-27396. DOI:10.1021/acsomega.4c02021

2982663-28-3 suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Website:	https://www.targetmol.cn/

Tags:2982663-28-3 Related Product Information