| Chemical Properties | Back Directory | [Boiling point ]
2116.542±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.249±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
4.004±0.10(predicted) | [color ]
White to off-white | [Sequence]
Ac-Tyr-His-Ile-Tyr-Tyr-Ala-Ser-Leu-Tyr-Gly-Asp-Leu-Gly-Cys-Gly-NH2 (Thioether bond between: Tyr1-Cys14) |
| Hazard Information | Back Directory | [Uses]
Lib2-1, a macrocyclic peptide, is an IL-17C/IL-17RE interaction inhibitor. Lib2-1 can be used for autoimmune and inflammatory diseases research[1]. | [References]
[1] Silong Zhai, et al. PepScaf: Harnessing Machine Learning with In Vitro Selection toward De Novo Macrocyclic Peptides against IL-17C/IL-17RE Interaction. J Med Chem. 2023 Aug 24;66(16):11187-11200. DOI:10.1021/acs.jmedchem.3c00627 |
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