| Identification | Back Directory | [Name]
Adenosine, 5′-[N-[(2S)-2-amino-3-hydroxy-1-oxopropyl]sulfamate] | [CAS]
299437-44-8 | [Synonyms]
Adenosine, 5′-[N-[(2S)-2-amino-3-hydroxy-1-oxopropyl]sulfamate] | [Molecular Formula]
C13H19N7O8S | [MOL File]
299437-44-8.mol | [Molecular Weight]
433.4 |
| Hazard Information | Back Directory | [Uses]
SerSA is a potent inhibitor of seryl-tRNA synthetases. SerSA inhibits EcSerRS, SaSerRS and HsSerRS with IC50s of 0.21, 0.23 and 2.17 μM, respectively[1]. | [References]
[1] Cain R, et al. Structure-Guided Enhancement of Selectivity of Chemical Probe Inhibitors Targeting Bacterial Seryl-tRNA Synthetase. J Med Chem. 2019 Nov 14;62(21):9703-9717. DOI:10.1021/acs.jmedchem.9b01131 |
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