| Identification | Back Directory | [Name]
1H-Isoindole-1,3(2H)-dione, 2-(2,3-dihydro-2-thioxo-6-benzothiazolyl)-4-nitro- | [CAS]
299922-10-4 | [Synonyms]
NIT
1H-Isoindole-1,3(2H)-dione, 2-(2,3-dihydro-2-thioxo-6-benzothiazolyl)-4-nitro- | [Molecular Formula]
C15H7N3O4S2 | [MOL File]
299922-10-4.mol | [Molecular Weight]
357.36 |
| Hazard Information | Back Directory | [Description]
NIT is an inhibitor of HIV-1 protease (HIV-1p). | [Uses]
NIT is an inhibitor of HIV-1 protease (HIV-1p) with Ki values of 96 and 91 μM for WT HIV-1p and MDR HIV-1p, respectively[1]. | [References]
[1] Ung PM, et al. An allosteric modulator of HIV-1 protease shows equipotent inhibition of wild-type and drug-resistant proteases. J Med Chem. 2014 Aug 14;57(15):6468-78. DOI:10.1021/jm5008352 |
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