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3001361-38-9

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3001361-38-9 Structure

3001361-38-9 Structure

Identification	Back Directory
[Name] MAO-A/SERT-IN-1
[CAS] 3001361-38-9
[Synonyms] MAO-A/SERT-IN-1
[Molecular Formula] C19H14N2O5
[MOL File] 3001361-38-9.mol
[Molecular Weight] 350.33

Chemical Properties	Back Directory
[Boiling point ] 612.9±50.0 °C(predicted)
[density ] 1.410±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 3.84±0.20(predicted)

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[Uses] MAO-A/SERT-IN-1 is an inhibitor of MAO-A/serotonin transporter (SERT). MAO-A/SERT-IN-1 can reduce SERT-mediated reuptake of 5-HT and has neuroprotective effects in cell inhibition models. MAO-A/SERT-IN-1 can improve depressive behavior in zebrafish and mice[1].
[IC 50] MAO-A
[References] [1] Zhong P, et al. Development of Nitric Oxide Releasing Oxoisoaporphines with Antidepressant Activities by Simultaneously Regulating MAO-A and SERT. J Med Chem. 2024 Sep 12;67(17):15509-15520. DOI:10.1021/acs.jmedchem.4c01161

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Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Website:	https://www.targetmol.cn/

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