| Identification | Back Directory | [Name]
1-Hexanol, 6,6'-oxybis[2,2-dimethyl- | [CAS]
300762-25-8 | [Synonyms]
Hydrocarbon chain derivative 1
6,6'-Oxybis[2,2-dimethyl-1-hexanol]
1-Hexanol, 6,6'-oxybis[2,2-dimethyl- | [Molecular Formula]
C16H34O3 | [MDL Number]
MFCD31544432 | [MOL File]
300762-25-8.mol | [Molecular Weight]
274.44 |
| Chemical Properties | Back Directory | [Boiling point ]
160-162 °C(Press: 0.15 Torr) | [density ]
0.933±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
14.91±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
Hydrocarbon chain derivative 1 is an active compound, with inhibitory activities against lipid synthesis. | [in vivo]
Hydrocarbon chain derivative 1 is well tolerated with mild liver effects at 2000 mg/kg in rats[1]. Hydrocarbon chain derivative 1 shows inhibitory effect on lipid synthesis, with an IC50 of 11 μM[2]. | [References]
[1] Oniciu DC, et al. Influence of various central moieties on the hypolipidemic properties of long hydrocarbon chain diols and diacids. J Med Chem. 2006 Jan 12;49(1):334-48. DOI:10.1021/jm050650j
[2] Oniciu DC, et al. Long hydrocarbon chain diols and diacids with central ether or ketone moieties that favorably alter lipid disorders. Pharmazie. 2006 Feb;61(2):157-65. PMID:16526566 |
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