| Identification | Back Directory | [Name]
(E)-3-(2-(2-hydroxy-3-methoxybenzylidene)hydrazinyl)-6-methyl-1,2,4-triazin-5-ol | [CAS]
301304-67-6 | [Synonyms]
(E)-3-(2-(2-hydroxy-3-methoxybenzylidene)hydrazinyl)-6-methyl-1,2,4-triazin-5-ol
Benzaldehyde, 2-hydroxy-3-methoxy-, 2-(2,5-dihydro-6-methyl-5-oxo-1,2,4-triazin-3-yl)hydrazone | [Molecular Formula]
C12H13N5O3 | [MOL File]
301304-67-6.mol | [Molecular Weight]
275.26 |
| Hazard Information | Back Directory | [Uses]
Antibacterial agent 227 (Compd 29) is a SerRS (Seryl-tRNA synthetase) inhibitor. Antibacterial agent 227 has a significant inhibitory effect on the growth of planktonic and biofilm culture of Staphylococcus aureus 25923 with MIC (minimum inhibitory concentration) value of 32?μg/ml. Antibacterial agent 227 can be proposed as effective antiseptic toward multidrug-resistant biofilm-forming S. aureus isolates[1]. | [References]
[1] Volynets GP, et al. Identification of novel antistaphylococcal hit compounds. J Antibiot (Tokyo). 2024 Jun 25. DOI:10.1038/s41429-024-00752-0 |
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PHARMEKS Ltd.
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+7 (495) 702-9648 |
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www.pharmeks.com |
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OTAVA chemicals
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416 305 9979 (Canada) |
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www.otavachemicals.com |
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