| Identification | Back Directory | [Name]
Dexsotalol | [CAS]
30236-32-9 | [Synonyms]
Dexsotalol
(S)-Sotalol
Dextrosotalol
N-[4-[(1S)-1-Hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]methanesulfonamide
Methanesulfonamide, N-[4-[(1S)-1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-
Methanesulfonamide, N-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-, (S)-
Methanesulfonamide, N-[4-[(1S)-1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]- (9CI) | [Molecular Formula]
C12H20N2O3S | [MOL File]
30236-32-9.mol | [Molecular Weight]
272.36 |
| Hazard Information | Back Directory | [Uses]
Cardiac depressant (anti-arrhythmic). | [in vivo]
(+)-Sotalol (8 mg/kg, i.v.) suppresses the induction of ventricular tachyarrhythmias by programmed stimulation in dogs[3].
| Animal Model: | Programmed stimulated Dogs[3] | | Dosage: | 8 mg/kg | | Administration: | Intravenous injection (i.v.) | | Result: | Increased normal zone ventricular refractoriness, and prevented propagation of programmed ventricular extra-stimuli of sufficient prematurity to elicit tachyarrhythmias. |
| [IC 50]
β-adrenoceptor |
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