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3023681-83-3

3023681-83-3 Structure

3023681-83-3 Structure
IdentificationBack Directory
[Name]

Benzamide, 2-(3,5-dichlorophenoxy)-N-[4-fluoro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]-
[CAS]

3023681-83-3
[Synonyms]

Benzamide, 2-(3,5-dichlorophenoxy)-N-[4-fluoro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]-
[Molecular Formula]

C18H11Cl2F4N3O2
[MOL File]

3023681-83-3.mol
[Molecular Weight]

448.2
Chemical PropertiesBack Directory
[Boiling point ]

436.9±45.0 °C(predicted)
[density ]

1.51±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

11.28±0.70(predicted)
Hazard InformationBack Directory
[Uses]

Succinate dehydrogenase-IN-2 (Compound 12x) is an inhibitor for succinate dehydrogenase (SDH) with an IC50 of 1.22 mg/L. Succinate dehydrogenase-IN-2 exhibits antifungal activity, that inhibits S. sclerotiorum, V. mali, G. graminis, R. solani and B. cinerea with EC50 of 0.52-3.42 mg/L[1].
[References]

[1] Xu D, et al., Discovery, Optimization, and Biological Evaluation of Novel Pyrazol-5-yl-phenoxybenzamide Derivatives as Potent Succinate Dehydrogenase Inhibitors. J Agric Food Chem. 2024 Jul 24. DOI:10.1021/acs.jafc.4c02685
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