| Identification | Back Directory | [Name]
Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl | [CAS]
3024909-50-7 | [Synonyms]
Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl
1H-Isoindole-1,3(2H)-dione, 5-[4-[[3-(3-bromophenyl)tetrahydro-2-oxo-1(2H)-pyrimidinyl]methyl]-1-piperidinyl]-2-(2,6-dioxo-3-piperidinyl)- | [Molecular Formula]
C29H30BrN5O5 | [MOL File]
3024909-50-7.mol | [Molecular Weight]
608.48 |
| Chemical Properties | Back Directory | [Boiling point ]
810.1±65.0 °C(predicted) | [density ]
1.509±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
10.83±0.40(predicted) |
| Hazard Information | Back Directory | [Uses]
Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl is an E3 Ligase Ligand-Linker Conjugate. Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl can be used to synthesize PROTAC GSPT1 degrader-2 (HY-159610)[1]. | [References]
[1] Tetrahydropyrimidine derivatives as GSPT1 degraders and their preparation. World Intellectual Property Organization, WO2024073871 A1. 2024-04-11. |
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