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3026790-18-8

3026790-18-8 Structure

3026790-18-8 Structure
IdentificationBack Directory
[Name]

3-Quinolinecarboxaldehyde, 2-chloro-6-methoxy-, 2-[4-(1-naphthalenyl)-2-thiazolyl]hydrazone
[CAS]

3026790-18-8
[Synonyms]

3-Quinolinecarboxaldehyde, 2-chloro-6-methoxy-, 2-[4-(1-naphthalenyl)-2-thiazolyl]hydrazone
[Molecular Formula]

C24H17ClN4OS
[MOL File]

3026790-18-8.mol
[Molecular Weight]

444.94
Chemical PropertiesBack Directory
[Boiling point ]

654.6±65.0 °C(predicted)
[density ]

1.37±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

8.00±0.10(predicted)
Hazard InformationBack Directory
[Uses]

Antibacterial agent 132 has anticandidal effects against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of <0.06 μg/mL and 62.50 μg/mL, respectively. Antibacterial agent 132 inhibits aromatase enzyme with an IC50 of 0.047μM[1].
[IC 50]

Aromatase
[References]

[1] Asaf Evrim Evren,et al. Investigation of Novel Quinoline-Thiazole Derivatives as Antimicrobial Agents: In Vitro and In Silico Approaches. ACS Omega. 2022 Dec 29;8(1):1410-1429. DOI:10.1021/acsomega.2c06871
Spectrum DetailBack Directory
[Spectrum Detail]

3-Quinolinecarboxaldehyde, 2-chloro-6-methoxy-, 2-[4-(1-naphthalenyl)-2-thiazolyl]hydrazone(3026790-18-8)1HNMR
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