| Identification | Back Directory | [Name]
3-Quinolinecarboxaldehyde, 2-chloro-6-methoxy-, 2-[4-(1-naphthalenyl)-2-thiazolyl]hydrazone | [CAS]
3026790-18-8 | [Synonyms]
3-Quinolinecarboxaldehyde, 2-chloro-6-methoxy-, 2-[4-(1-naphthalenyl)-2-thiazolyl]hydrazone | [Molecular Formula]
C24H17ClN4OS | [MOL File]
3026790-18-8.mol | [Molecular Weight]
444.94 |
| Hazard Information | Back Directory | [Uses]
Antibacterial agent 132 has anticandidal effects against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of <0.06 μg/mL and 62.50 μg/mL, respectively. Antibacterial agent 132 inhibits aromatase enzyme with an IC50 of 0.047μM[1]. | [IC 50]
Aromatase | [References]
[1] Asaf Evrim Evren,et al. Investigation of Novel Quinoline-Thiazole Derivatives as Antimicrobial Agents: In Vitro and In Silico Approaches. ACS Omega. 2022 Dec 29;8(1):1410-1429. DOI:10.1021/acsomega.2c06871 |
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