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PDE11A4-IN-1 (compound 23b) is a potent and selective PDE11A4 inhibitor with an IC50 of 12 nM. PDE11A4-IN-1 show high selectivity for PDE11A4 over PDE1, PDE2, PDE7, PDE8, and PDE9[1]. | [IC 50]
PDE11A4: 12 nM (IC50) | [References]
[1] Shams Ul Mahmood, et al. First Optimization of Novel, Potent, Selective PDE11A4 Inhibitors for Age-Related Cognitive Decline. J Med Chem. 2023 Oct 20. DOI:10.1021/acs.jmedchem.3c01088 |
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| Company Name: |
Invivochem
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| Telephone: |
13829706226 |
| Website: |
www.invivochem.cn |
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