| Identification | Back Directory | [Name]
[Tyr3]Octreotate acetate | [CAS]
302794-43-0 | [Synonyms]
Tyr3]Octreotate
[Tyr3]Octreotate acetate
[TYR3]OCTREOTATE ACETATE > 95 %
L-Threonine, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide | [Molecular Formula]
C49H64N10O12S2 | [MOL File]
302794-43-0.mol | [Molecular Weight]
1049.23 |
| Chemical Properties | Back Directory | [Boiling point ]
1496.4±65.0 °C(Predicted) | [density ]
1.44±0.1 g/cm3(Predicted) | [pka]
3.18±0.10(Predicted) | [Sequence]
{d-Phe}-Cys-Tyr-{d-Trp}-Lys-Thr-Cys-Thr (Disulfide bridge: Cys2-Cys7) |
| Hazard Information | Back Directory | [Uses]
Tyr3-Octreotate is a somatostatin analog. Tyr3-Octreotate exhibits high uptake into tumor, that is capable to be labeled with radioactive metal and thus exhibits antitumor efficacy. Tyr3-Octreotate can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs)[1]. | [References]
[1] Capello A, et al., Tyr3-octreotide and Tyr3-octreotate radiolabeled with 177Lu or 90Y: peptide receptor radionuclide therapy results in vitro. Cancer Biother Radiopharm. 2003 Oct;18(5):761-8. |
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