| Identification | Back Directory | [Name]
ATOCALCITOL | [CAS]
302904-82-1 | [Synonyms]
ATOCALCITOL
Altocalciferol
(1S,3R,5Z,7E,20R)-20-(3-(2-Hydroxypropan-2-yl)benzyloxymethyl)-9,10-secopregna-5,7,10(19)-triene-1alpha,3beta-diol
1,3-Cyclohexanediol,4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-2-[[3-(1-hydroxy-1-Methylethyl)phenyl]Methoxy]-1-Methylethyl]-7a-Methyl-4H-inden-4-ylidene]ethylidene]-,(1R,3S,5Z)-
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-1-[[3-(2-hydroxypropan-2-yl)phenyl]methoxy]propan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol | [Molecular Formula]
C32H46O4 | [MDL Number]
MFCD09838285 | [MOL File]
302904-82-1.mol | [Molecular Weight]
494.71 |
| Chemical Properties | Back Directory | [Boiling point ]
636.3±55.0 °C(Predicted) | [density ]
1.12±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
14.43±0.29(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Atocalcitol, a vitamin D3 analogue, is used in the study for psoriasis[1]. | [Definition]
ChEBI: Atocalcitol is a vitamin D. | [References]
[1] Xuan Xu, et al. The Immunogenetics of Psoriasis and Implications for Drug Repositioning. Int J Mol Sci. 2017 Dec 8;18(12):2650. DOI:10.3390/ijms18122650
[2] Nicklas H Staunstrup, et al. A Sleeping Beauty DNA transposon-based genetic sensor for functional screening of vitamin D3 analogues. BMC Biotechnol. 2011 Apr 7;11:33. DOI:10.1186/1472-6750-11-33 |
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