| Identification | Back Directory | [Name]
Benzenemethanol, 3-fluoro-2-methoxy- (9CI) | [CAS]
303043-91-6 | [Synonyms]
3-Fluoro-2-Methoxy-benzeneMethanol
(3-Fluoro-2-Methoxyphenyl)Methanol
Benzenemethanol, 3-fluoro-2-methoxy-
Benzenemethanol, 3-fluoro-2-methoxy- (9CI) | [Molecular Formula]
C8H9FO2 | [MDL Number]
MFCD09025369 | [MOL File]
303043-91-6.mol | [Molecular Weight]
156.15 |
| Chemical Properties | Back Directory | [Boiling point ]
236.5±25.0 °C(Predicted) | [density ]
1.187±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
14.09±0.10(Predicted) | [Appearance]
Light yellow to yellow Liquid |
| Hazard Information | Back Directory | [Uses]
3-Fluoro-2-methoxybenzenemethanol | [Synthesis]
General procedure for the synthesis of 3-fluoro-2-methoxy-benzenemethanol from 3-fluoro-2-methoxybenzaldehyde: To a solution of 3-fluoro-2-methoxybenzaldehyde (3.41 g, 22.1 mmol) in methanol (20 mL) was slowly added sodium borohydride (1.00 g, 26.6 mmol) under nitrogen protection. The reaction mixture was stirred overnight at room temperature. After completion of the reaction, the reaction mixture was diluted with ether, washed twice sequentially with water, the organic phase was dried with anhydrous sodium sulfate, filtered and concentrated to give 3.02 g (87% yield) of 3-fluoro-2-methoxy-benzenemethanol as a clear colorless oil. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 7.09-6.92 (m, 3H), 4.65 (d, 2H), 3.97 (s, 3H), 2.14 (t, 1H, OH). | [References]
[1] Patent: WO2009/140448, 2009, A1. Location in patent: Page/Page column 39 |
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| Company Name: |
SynAsst Chemical.
|
| Tel: |
021-60343070 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15848/0_EN.htm |
| Company Name: |
Cool Pharm, Ltd
|
| Tel: |
021-58581007 18019463053 |
| Website: |
http://www.coolpharm.com.cn |
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