| Chemical Properties | Back Directory | [Boiling point ]
710.6±60.0 °C(predicted) | [density ]
1.58±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
2.81±0.50(predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
SPOP-IN-2 (compound E1) is a Speckle-type POZ protein (SPOP) inhibitor with IC50 of 0.58 μM, which disrupt the SPOP-subtrate interaction and selectively inhibits proliferation of ccRCC[1]. | [References]
[1] Zhou C, et al., Synthesis and Biological Evaluation of β-Lactam Derivatives Targeting Speckle-Type POZ Protein (SPOP). ACS Med Chem Lett. 2024 Jan 25;15(2):270-279. DOI:10.1021/acsmedchemlett.3c00515 |
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| Company Name: |
TargetMol
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| Telephone: |
400-821-0310 15002144251 |
| Website: |
www.targetmol.cn/ |
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