| Hazard Information | Back Directory | [Uses]
PDE3B-IN-1 is a selective inhibitor for phosphodiesterase PDE3B with an IMAP pIC50 of 6.5 and a PDE3B/A selective index >300[1]. | [IC 50]
PDE3B: 6.5 μM (IC50) | [References]
[1] Rowley AM, et al., Discovery and SAR Study of Boronic Acid-Based Selective PDE3B Inhibitors from a Novel DNA-Encoded Library. J Med Chem. 2024 Feb 8;67(3):2049-2065. DOI:10.1021/acs.jmedchem.3c01562 |
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