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3032733-05-1

3032733-05-1 Structure

3032733-05-1 Structure
IdentificationBack Directory
[Name]

LRRK2-IN-12
[CAS]

3032733-05-1
[Synonyms]

LRRK2-IN-12
[Molecular Formula]

C18H17ClN8O2
[MOL File]

3032733-05-1.mol
[Molecular Weight]

412.83
Chemical PropertiesBack Directory
[Boiling point ]

681.0±65.0 °C(predicted)
[density ]

1.65±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

2.04±0.20(predicted)
Hazard InformationBack Directory
[Uses]

LRRK2-IN-12 (compound 1) inhibits the activity of LRRK2 G20195 (IC50=0.45 nM), LRRK2 WT (IC50=1.1 nM) and LRRK2 WT ADP-Glo (IC50=0.46 nM). LRRK2-IN-12 can be used for Alzheimer's Disease research[1].
[References]

[1] Thomas Jensen, et al. Macrocyclic leucine-rich repeat kinase 2 (lrrk2) inhibitors.WO2024056775A1.2023-09-14
3032733-05-1 suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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