3033865-28-7

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3033865-28-7 Structure

Chemical Properties	Back Directory
[Boiling point ] 900.1±65.0 °C(predicted)
[density ] 1.44±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 7.79±0.60(predicted)

Hazard Information	Back Directory
[Uses] N,N-Dimethyl-idarubicin-trisaccharide (compound 26) is an efficient intercalating agent. N,N-Dimethyl-idarubicin-trisaccharide shows excellent cytotoxicity against ABCG2-overexpressing and ABCB1-overexpressing cells with IC50s of 19 and 32 nM, respectively[1].
[References] [1] van Gelder M A, et al. Novel N, N-Dimethyl-idarubicin Analogues Are Effective Cytotoxic Agents for ABCB1-Overexpressing, Doxorubicin-Resistant Cells[J]. Journal of Medicinal Chemistry, 2024.

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