3036158-98-9

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3036158-98-9 Structure

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[Uses] PF-07853578 (Example 11) is a PNPLA3 degrader with an EC50 of 8 nM. PNPLA3 degrader-1 can be used in the study of cirrhosis and hepatocellular carcinoma[1].
[References] [1] Christopher William Am Ende, et al. Patatin-like phospholipase domain-containing protein 3 (pnpla3) modifiers. WO, WO2024084360A1. 2024-04-25

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