| Identification | Back Directory | [Name]
PROTAC BRD4-DCAF1 degrader-1 | [CAS]
3036944-87-0 | [Synonyms]
PROTAC BRD4-DCAF1 degrader-1
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, N-[18-[4-[[4-[[[(1S)-3-amino-1-(3-chlorophenyl)-3-oxopropyl]amino]carbonyl]-3-(3,6-difluoro-2-methylphenyl)-1H-pyrrol-2-yl]carbonyl]phenyl]-3,6,9,12,15-pentaoxaoctadec-1-yl]-4-(4-chlorophenyl)-2,3,9-trimethyl-, (6S)- | [Molecular Formula]
C60H64Cl2F2N8O9S | [MOL File]
3036944-87-0.mol | [Molecular Weight]
1182.17 |
| Hazard Information | Back Directory | [Uses]
PROTAC BRD4-DCAF1 degrader-1 (I-907) is a BRD4-DCAF1 PROTAC degrader, DC50 is 10~100 nM. (Pink: BRD4-DCAF1 ligand (HY-169152); Black: linker (HY-126976); Blue: E3 ligase ligand (HY-15846))[1]. | [References]
[1] Lewis Dale Pennington, et al. Protein degraders and uses thereof. WO2024092009A1. 2024-05-02. |
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