| Identification | Back Directory | [Name]
8-Quinolinesulfonamide, N-[[1-(7-chloro-4-quinolinyl)-1H-1,2,3-triazol-4-yl]methyl]-N-methyl- | [CAS]
3039831-27-8 | [Synonyms]
8-Quinolinesulfonamide, N-[[1-(7-chloro-4-quinolinyl)-1H-1,2,3-triazol-4-yl]methyl]-N-methyl- | [Molecular Formula]
C22H17ClN6O2S | [MOL File]
3039831-27-8.mol | [Molecular Weight]
464.93 |
| Hazard Information | Back Directory | [Uses]
Anticancer agent 240 (compound 9b) is an 8-quinolinesulfonamide derivative with a cytotoxicity activity. Anticancer agent 240 shows inhibitory activity in Caco-2, SNB-19, A-549, and SKOV-3 cell line IC50 values of 0.26, 0.38, 0.40 and 4.16 μM[1]. | [References]
[1] Krzysztof Marciniec, et al. Synthesis, Docking, and Machine Learning Studies of Some Novel Quinolinesulfonamides-Triazole Hybrids with Anticancer Activity. Molecules. 2024 Jul 2;29(13):3158. DOI:10.3390/molecules29133158 |
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