| Identification | Back Directory | [Name]
EBOV-IN-10 | [CAS]
3040400-51-6 | [Synonyms]
EBOV-IN-10
2-Thiophenecarboxamide, N-phenyl-5-[4-(4-piperidinyloxy)phenyl]- | [Molecular Formula]
C22H22N2O2S | [MOL File]
3040400-51-6.mol | [Molecular Weight]
378.49 |
| Chemical Properties | Back Directory | [Boiling point ]
507.0±50.0 °C(predicted) | [density ]
1.238±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
12.46±0.70(predicted) |
| Hazard Information | Back Directory | [Uses]
EBOV-IN-10 is an orally active Ebola virus (EBOV) inhibitor with an EC50 value of 0.19 μM[1]. | [References]
[1] Morales-Tenorio M, et al. Discovery of Thiophene Derivatives as Potent, Orally Bioavailable, and Blood-Brain Barrier-Permeable Ebola Virus Entry Inhibitors. J Med Chem. 2024 Sep 9. DOI:10.1021/acs.jmedchem.4c01267 |
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