| Identification | Back Directory | [Name]
4'-chloro-6-(4-morpholinobut-1-yn-1-yl)-3'-(trifluoromethyl)-3-(3-(trifluoromethyl)-1H-pyrazol-5-yl)-[1,1'-biphenyl]-2-ol | [CAS]
3042878-82-7 | [Synonyms]
RMA-95
4'-chloro-6-(4-morpholinobut-1-yn-1-yl)-3'-(trifluoromethyl)-3-(3-(trifluoromethyl)-1H-pyrazol-5-yl)-[1,1'-biphenyl]-2-ol
4'-chloro-6-(4-morpholinobut-1-yn-1-yl)-3'-(trifluoromethyl)-3-(3-(trifluoromethyl)-1H-pyrazol-5-yl)-[1,1'-biphenyl]-2-ol | [Molecular Formula]
C25H20ClF6N3O2 | [MOL File]
3042878-82-7.mol | [Molecular Weight]
543.89 |
| Chemical Properties | Back Directory | [Boiling point ]
627.9±55.0 °C(predicted) | [density ]
1.51±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
4.18±0.10(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
MYC-IN-3 (compound 37) is a potent MYC inhibitor. MYC-IN-3 shows antiproliferative activity. MYC-IN-3 shows anticancer activity. MYC-IN-3 has the potential for the research of prostate cancer[1]. | [References]
[1] Zhao C, et al. Directly Suppressing MYC Function with Novel Alkynyl-Substituted Phenylpyrazole Derivatives that Induce Protein Degradation and Perturb MYC/MAX Interaction. J Med Chem. 2024 Jul 11. DOI:10.1021/acs.jmedchem.4c00272 |
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