| Chemical Properties | Back Directory | [Boiling point ]
663.0±65.0 °C(predicted) | [density ]
1.67±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
1.67±0.10(predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
Polθ-IN-4 (Example 1) is a DNA polymerase theta (Polθ) inhibitor that inhibits Polθ activity by targeting its ATP-dependent helicase domain. Polθ-IN-4 can be utilized in cancer research[1]. | [References]
[1] Janos B, et al. Thiadiazolyl derivatives as dna polymerase theta inhibitors and uses thereof, WO2024121290A1, 2024-06-13 |
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