3046390-54-6

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3046390-54-6 Structure

Identification	Back Directory
[Name] Benzamide, 2,4,6-trichloro-N-[4-[[4-(1-methylethyl)-1-piperazinyl]sulfonyl]phenyl]-
[CAS] 3046390-54-6
[Synonyms] Benzamide, 2,4,6-trichloro-N-[4-[[4-(1-methylethyl)-1-piperazinyl]sulfonyl]phenyl]-
[Molecular Formula] C20H22Cl3N3O3S
[MOL File] 3046390-54-6.mol
[Molecular Weight] 490.83

Chemical Properties	Back Directory
[density ] 1.432±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 10.71±0.70(predicted)

Hazard Information	Back Directory
[Uses] TRPV4-IN-5 (Compound 1f) is a potent TRPV4 inhibitor (IC50 = 0.46 μM). TRPV4-IN-5 significantly alleviates the symptoms of acute lung injury induced by lipopolysaccharide (HY-D1056) in mice[1].
[IC 50] TRPV4: 0.46 μM (IC₅₀)
[References] [1] Wang M, et al. Exploration and structure-activity relationship research of benzenesulfonamide derivatives as potent TRPV4 inhibitors for treating acute lung injury. Bioorg Chem. 2024 Jun;147:107396. DOI:10.1016/j.bioorg.2024.107396

3046390-54-6 suppliers list

Company Name:	Shanghai Beckham Medical Technology Co., Ltd
Tel:	13816613772
Website:	www.chemicalbook.com/ShowSupplierProductsList16976/0_EN.htm

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