| Identification | Back Directory | [Name]
2,4-Pentanedione,3-[(4-hydroxy-3-methoxyphenyl)methyl]- | [CAS]
30881-23-3 | [Synonyms]
3-(4-hydroxy-3-methoxybenzyl)pentane-2,4-dione
3-[(4-hydroxy-3-methoxyphenyl)methyl]pentane-2,4-dione
2,4-Pentanedione,3-[(4-hydroxy-3-methoxyphenyl)methyl]- | [EINECS(EC#)]
820-605-0 | [Molecular Formula]
C13H16O4 | [MOL File]
30881-23-3.mol | [Molecular Weight]
236.26 |
| Chemical Properties | Back Directory | [Boiling point ]
250℃ at 101.325kPa | [density ]
0.494g/cm3 at 20℃ | [vapor pressure ]
0Pa at 25℃ | [form ]
Solid:particulate/powder | [pka]
9.87±0.20(Predicted) | [Cosmetics Ingredients Functions]
ANTIOXIDANT
CHELATING
SKIN PROTECTING | [InChI]
InChI=1S/C13H16O4/c1-8(14)11(9(2)15)6-10-4-5-12(16)13(7-10)17-3/h4-5,7,11,16H,6H2,1-3H3 | [InChIKey]
IFGDRUTWCITGHG-UHFFFAOYSA-N | [SMILES]
CC(=O)C(CC1=CC=C(O)C(OC)=C1)C(=O)C | [LogP]
1.43 at 20℃ and pH5.99 | [Surface tension]
61.75mN/m at 1g/L and 20℃ |
| Hazard Information | Back Directory | [Uses]
Acetyl zingerone is a new multifunctional skincare ingredient that protects melanocytes from ongoing DNA damage. Acetyl zingerone inhibits matrix metalloproteinases and suppresses the expression of the IL-17A target genes, having anti-inflammatory and antioxidant activities[1][2]. | [References]
[1] William R Swindell, et al. A Zingerone Analog, Acetyl Zingerone, Bolsters Matrisome Synthesis, Inhibits Matrix Metallopeptidases, and Represses IL-17A Target Gene Expression. J Invest Dermatol. 2020 Mar;140(3):602-614.e15. DOI:10.1016/j.jid.2019.07.715
[2] R K Chaudhuri, et al. Acetyl zingerone: An efficacious multifunctional ingredient for continued protection against ongoing DNA damage in melanocytes after sun exposure ends. Int J Cosmet Sci. 2020 Feb;42(1):36-45. DOI:10.1111/ics.12582 |
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| Company Name: |
Puripharm Co., Ltd.
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| Tel: |
0572-2745768-1 13167223168 |
| Website: |
http://www.puriactives.com/ |
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