| Identification | Back Directory | [Name]
8-Epixanthatin | [CAS]
30890-35-8 | [Synonyms]
8-Epixanthatin
2H-Cyclohepta[b]furan-2-one, 3,3a,4,7,8,8a-hexahydro-7-methyl-3-methylene-6-[(1E)-3-oxo-1-buten-1-yl]-, (3aR,7S,8aR)- | [Molecular Formula]
C15H18O3 | [MOL File]
30890-35-8.mol | [Molecular Weight]
246.3 |
| Chemical Properties | Back Directory | [Boiling point ]
444.297±45.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.108±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [color ]
White to off-white | [InChI]
InChI=1S/C15H18O3/c1-9-8-14-13(11(3)15(17)18-14)7-6-12(9)5-4-10(2)16/h4-6,9,13-14H,3,7-8H2,1-2H3/b5-4+/t9-,13+,14+/m0/s1 | [InChIKey]
RBRPTFMVULVGIC-MDKNCZOUSA-N | [SMILES]
O1C(=O)C(=C)[C@@]2([H])CC=C(/C=C/C(=O)C)[C@@H](C)C[C@@]12[H] |
| Hazard Information | Back Directory | [Uses]
8-?Epixanthatin has been known to induce apoptosis of DU145 prostate carcinoma cells. | [in vivo]
8-Epixanthatin (i.p., 50 mg/kg, 5 days per week for 25 days) can inhibit tumor growth through STAT3 inactivation, the tumor volume of mice was reduced by 40.1%, the tumor weight was reduced by 40.0%, and the p-STAT3 level in the tumor was significantly reduced in the mouse xenograft model of DU145 cells[1].
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| Company Name: |
Shaanxi Dideu Medichem Co. Ltd
|
| Telephone: |
+86-029-81138252 +86-173 9270 1263 |
| Website: |
https://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-222/ |
| Company Name: |
cjbscvictory
|
| Telephone: |
13348960310 13348960310 |
| Website: |
www.weikeqi-biotech.com/ |
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