| Identification | Back Directory | [Name]
GW791343 HCl | [CAS]
309712-55-8 | [Synonyms]
GW791343 3HCl
GW791343 HCl USP/EP/BP
GW791343 (trihydrochloride)
GW 791343 TRIHYDROCHLORIDE; GW-791343 TRIHYDROCHLORIDE;
2-(3,4-difluorophenylamino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide trihydrochloride
2-((3,4-difluorophenyl)amino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide hydrogen chloride | [Molecular Formula]
C20H24F2N4O.3(HCl) | [MOL File]
309712-55-8.mol | [Molecular Weight]
483.81 |
| Hazard Information | Back Directory | [Uses]
GW 791343 Trihydrochloride is a P2X7 receptor antagonist that acts as an allosteric inhibitor, exhibiting negative allosteric effects at the human P2X7 receptor and positive allosteric effects at the rat P2X7 receptor. P2X7 receptor is responsible for the presence of inflammatory cells, regulated by extracellular ATP. | [IC 50]
P2X7 Receptor: 6.9-7.2 (pIC50) | [storage]
Store at -20°C |
|
| Company Name: |
NCE Biomedical Co.,Ltd.
|
| Telephone: |
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15748/0_EN.htm |
| Company Name: |
LETOPHARM LIMITED
|
| Telephone: |
+86-21-5821 5861 |
| Website: |
www.letopharm.com |
| Company Name: |
SPIRO PHARMA
|
| Telephone: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|