| Identification | Back Directory | [Name]
ARG-GLU(EDANS)-(ASN670,LEU671)-APP770 (668-675)-LYS(DABCYL)-ARG | [CAS]
310427-94-2 | [Synonyms]
ARG-GLU(EDANS)-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-LYS(DABCYL)-ARG
ARG-GLU(EDANS)-(ASN670,LEU671)-APP770 (668-675)-LYS(DABCYL)-ARG
H-ARG-GLU(EDANS)-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-LYS(DABCYL)-ARG-OH
Arg-Glu: EDANS-: Asn670,Leu671-Amyloid b/A4 Protein Precursor770: 668-675-Lys: DABCYL-Arg
Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg
ARG-GLU(EDANS)-(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (668-675)-LYS (DABCYL)-ARG
ARG-GLU(EDANS)-[ASN670, LEU671]-AMYLOID B/A4 PROTEIN PRECURSOR 770 FRAGMENT 669-674-(DABCYL)LYS-ARG
Arg-Glu(EDANS)-[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 669-674-(DABCYL)Lys-Arg
Arg-Glu(EDANS)-[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 669-674-(DABCYL)Lys-Arg
Arg-Glu(EDANS)-(Asn???,Leu??1)-Amyloid β/A4 Protein Precursor??? (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt
Arg-Glu(EDANS)-(Asn???,Leu???)-Amyloid β/A4 Protein Precursor??? (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt
Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid beta/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt
L-Arginyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-glutaminyl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-[4-[2-[4-(dimethylamino)phenyl]diazenyl]benzoyl]-L-lysyl-L-arginine
L-Arginine, L-arginyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-glutaminyl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-[4-[2-[4-(dimethylamino)phenyl]diazenyl]benzoyl]-L-lysyl- | [Molecular Formula]
C91H129N25O25S | [MDL Number]
MFCD03093396 | [MOL File]
310427-94-2.mol | [Molecular Weight]
2005.22 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C | [solubility ]
DMSO: 5mg/mL | [form ]
solid | [color ]
red | [Sequence]
Arg-{Glu(EDANS)}-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-{Lys(DABCYL)}-Arg |
| Hazard Information | Back Directory | [Uses]
RE (EDANS) EVNLDAEFK (DABCYL) R is an EDANS and DABCYL double-labeled peptide，serves as a fluorescent substrate for BACE1(Em=360nm，Ex=528nm). RE (EDANS) EVNLDAEFK (DABCYL) R can be used for BACE1 activity measurement and the enzyme activity level is directly proportional to the fluorescence reaction[1]. | [Biological Activity]
Cell permeable: no''Primary Target
β-secretase substrate''Product does not compete with ATP.''Reversible: no | [References]
[1] Ortega A, et.al. Synthesis and evaluation of arylquinones as BACE1 inhibitors, β-amyloid peptide aggregation inhibitors, and destabilizers of preformed β-amyloid fibrils. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2183-7. DOI:10.1016/j.bmcl.2011.03.023 |
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