| Identification | Back Directory | [Name]
5-CHLORO-2-FORMYLPYRIDINE | [CAS]
31181-89-2 | [Synonyms]
5-chloropicolinaldehyde
5-CHLORO-2-FORMYLPYRIDINE
5-Chloropyridine-2-carbaldehyde
5-Chloro-2-pyridinecarbaldehyde
Picolinaldehyde,5-chloro- (8CI)
5-Chloropyridine-2-carboxaldehyde
5-Chloro-2-pyridinecarboxaldehyde
2-Pyridinecarboxaldehyde, 5-chloro-
5-Chloro-2-Formylpyridine(WX624172)
5-Chloropyridine-2-carbaldehyde, 97+%
5-Chloro-2-pyridinecarboxaldehyde >
5-CHLORO-2-FORMYLPYRIDINE ISO 9001：2015 REACH
5-Chloro-2-formylpyridine, 5-Chloropicolinaldehyde | [EINECS(EC#)]
695-967-4 | [Molecular Formula]
C6H4ClNO | [MDL Number]
MFCD08277271 | [MOL File]
31181-89-2.mol | [Molecular Weight]
141.56 |
| Chemical Properties | Back Directory | [Melting point ]
66-68° | [Boiling point ]
208℃ | [density ]
1.332 | [Fp ]
79℃ | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
soluble in Methanol | [form ]
powder to crystal | [pka]
1.44±0.10(Predicted) | [color ]
White to Yellow to Orange | [InChI]
InChI=1S/C6H4ClNO/c7-5-1-2-6(4-9)8-3-5/h1-4H | [InChIKey]
YYLBDBOSXXSZQQ-UHFFFAOYSA-N | [SMILES]
C1(C=O)=NC=C(Cl)C=C1 |
| Hazard Information | Back Directory | [Synthesis]
Ethyl 5-chloropyridine-2-carboxylate (146 mg, 76% yield) was obtained by reacting 5-chloropyridine-2-carboxylic acid (200 mg, 1.03 mmol) in ethanol (3 mL) and a dioxane solution (0.5 mL) of 4M HCl at 90 °C for 20 hours. Subsequently, ethyl 5-chloropyridine-2-carboxylate (146 mg, 0.786 mmol) was dissolved in dichloromethane (4.0 mL), to which a toluene solution of 1M DIBAL (1.74 mL, 1.74 mmol) was added and reacted for 20 min to give 5-chloropyridine-2-carbaldehyde (58 mg, 52% yield). The product was analyzed by GC-MS and the molecular ion peak (M+) was 141. | [References]
[1] Patent: WO2004/14902, 2004, A2. Location in patent: Page 42 |
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