| Chemical Properties | Back Directory | [Boiling point ]
654.0±55.0 °C(Predicted) | [density ]
1.54±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
6.76±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
Dehydroaltenusin is derived from Trifluoromethanesulfonic Acid 7-Methoxy-2,2-dimethyl-4-oxo-4H-1,3-benzodioxin-5-yl Ester (T790530), which is an intermediate for the synthesis of precursor compound for Altenuene (A575740), a toxin isolated from the fungus Alternaria tenuis. | [in vivo]
Dehydroaltenusin (injection; 20 mg/kg; 2-day intervals; 12-39 days) shows suppressed tumor growth from 21 days[1]. | Animal Model: | Nude mice bearing HeLa solid tumors[1] | | Dosage: | 20 mg/kg | | Administration: | Injection; 20 mg/kg; 2-day intervals; 12-39 days | | Result: | Suppressed tumor growth. |
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