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312275-43-7

312275-43-7 Structure

312275-43-7 Structure
IdentificationBack Directory
[Name]

2-(5-bromo-2-hydroxy-3-iodobenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one
[CAS]

312275-43-7
[Synonyms]

2-(5-bromo-2-hydroxy-3-iodobenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one
Thiazolo[3,2-a]benzimidazol-3(2H)-one, 2-[(5-bromo-2-hydroxy-3-iodophenyl)methylene]-
[Molecular Formula]

C16H8BrIN2O2S
[MOL File]

312275-43-7.mol
[Molecular Weight]

499.12
Chemical PropertiesBack Directory
[Boiling point ]

585.6±60.0 °C(Predicted)
[density ]

2.16±0.1 g/cm3(Predicted)
[pka]

6.57±0.50(Predicted)
Hazard InformationBack Directory
[Uses]

SIRT2-IN-15 (compound 1) is a SIRT2 deacetylase and deamyloacylase inhibitor with IC50 B > 7 and 37 μM, respectively[1].
[References]

[1] Yang J, et al. A homogeneous time-resolved fluorescence screen to identify SIRT2 deacetylase and defatty-acylase inhibitors. PLoS One. 2024 Jun 24;19(6):e0305000. DOI:10.1371/journal.pone.0305000
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