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312752-00-4

312752-00-4 Structure

312752-00-4 Structure
IdentificationBack Directory
[Name]

RPRAATF-NH2
[CAS]

312752-00-4
[Synonyms]

RPRAATF
RPRAATF-NH2
AKT SUBSTRATE
RAC KINASE SUBSTRATE
PROTEIN KINASE B (ALPHA)
AKT/SGK SUBSTRATE PEPTIDE
PROTEIN KINASE BALPHA SUBSTRATE
[Molecular Formula]

C36H60N14O8
[MDL Number]

MFCD04974584
[MOL File]

312752-00-4.mol
[Molecular Weight]

816.95
Chemical PropertiesBack Directory
[density ]

1.477±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[storage temp. ]

-20°C
[form ]

lyophilized
[pka]

13.287±0.46(predicted)
[Sequence]

Arg-Pro-Arg-Ala-Ala-Thr-Phe-NH2
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

AKT refers to the serine/threonine protein kinases, AKT-1, AKT-2 and AKT-3, which are involved in the cellular processes of glucose metabolism, cell proliferation, apoptosis, transcription and cell migration. The peptide Arg-Pro-Arg-Ala-Ala-Thr-Phe may be a relatively specific substrate for PKBα (AKT-1) because, unlike other substrates, it is not phosphorylated by p70 S6 kinase or MAP kinase activated protein (MAPKAP) kinase-1.
[Biological Activity]

Protein Target: Akt''Target Sub-Family: AGC
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