| Identification | Back Directory | [Name]
panepoxydone | [CAS]
31298-54-1 | [Synonyms]
Panepoxydone from Lentinus conatus, >=95% (HPLC)
(1S,6S)-5β-Hydroxy-3-[(R)-1-hydroxy-3-methyl-2-butenyl]-7-oxabicyclo[4.1.0]hept-3-en-2-one
(1β,6β)-3-[(1R)-1-Hydroxy-3-methyl-2-butenyl]-5β-hydroxy-7-oxabicyclo[4.1.0]hepta-3-ene-2-one
(1S,5R,6S)-5-Hydroxy-3-[(1S)-1-hydroxy-3-methyl-2-buten-1-yl]-7-oxabicyclo[4.1.0]hept-3-en-2-one
7-Oxabicyclo[4.1.0]hept-3-en-2-one, 5-hydroxy-3-[(1S)-1-hydroxy-3-methyl-2-buten-1-yl]-, (1S,5R,6S)- | [Molecular Formula]
C11H14O4 | [MOL File]
31298-54-1.mol | [Molecular Weight]
210.23 |
| Chemical Properties | Back Directory | [Boiling point ]
437.9±45.0 °C(Predicted) | [density ]
1.338±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO: soluble10mg/mL | [form ]
powder | [pka]
12.67±0.40(Predicted) | [biological source]
Lentinus conatus | [InChI]
1S/C11H14O4/c1-5(2)3-7(12)6-4-8(13)10-11(15-10)9(6)14/h3-4,7-8,10-13H,1-2H3/t7?,8-,10+,11-/m1/s1 | [InChIKey]
MBXKEYXHJAZKBP-VQZXEUHYSA-N |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS06 | [Signal word ]
Danger | [Hazard statements ]
H301 | [Precautionary statements ]
P301+P310 | [Hazard Codes ]
T | [Risk Statements ]
25 | [Safety Statements ]
45 | [RIDADR ]
UN 2811 6.1 / PGIII | [WGK Germany ]
3 | [Storage Class]
6.1D - Non-combustible acute toxic Cat.3
toxic hazardous materials or hazardous materials causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral |
| Hazard Information | Back Directory | [Biochem/physiol Actions]
Panepoxydone is a fungal metabolite that inhibits NF-κB transcription factor by preventing IκB phosphorylation, thus inhibiting the release of NF-κB from the IκB : NF-κB complex and its translocation into the nucleus. Panepoxydone also has antimalarial, cytotoxic activities and anti-parasitic activity against Trypanosoma cruzi. |
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