ChemicalBook--->CAS DataBase List--->313480-47-6

313480-47-6

313480-47-6 Structure

313480-47-6 Structure
IdentificationBack Directory
[Name]

N-(1,3-benzothiazol-2-yl)-3,3-diphenylpropanamide
[CAS]

313480-47-6
[Synonyms]

Benzenepropanamide, N-2-benzothiazolyl-β-phenyl-
N-(1,3-benzothiazol-2-yl)-3,3-diphenylpropanamide
[Molecular Formula]

C22H18N2OS
[MDL Number]

MFCD01196557
[MOL File]

313480-47-6.mol
[Molecular Weight]

358.46
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 250 mg/mL (697.43 mM; Need ultrasonic)
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

IGS-1.76 efficiently inhibits the human NCS-1/Ric8a complex. IGS-1.76 shows a significantly increased affinity for hNCS-1 and is able to modulate the hNCS-1/Ric8a interaction efficiently[1].
[Biological Activity]

IGS-1.76 efficiently inhibits the human NCS-1/Ric8a complex. IGS-1.76 shows a significantly increased affinity for hNCS-1 and is able to modulate the hNCS-1/Ric8a interaction efficiently[1]. IGS-1.76 is a Drosophila NCS-1/IGS-1.76 complex inhibitor[1].
[storage]

Store at -20°C
[References]

[1]. Carlos Roca, et al. Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators. J Med Chem. 2018 Jul 26;61(14):5910-5921.
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