ChemicalBook--->CAS DataBase List--->31356-94-2

31356-94-2

31356-94-2 Structure

31356-94-2 Structure
IdentificationBack Directory
[Name]

8-BR-CGMP
[CAS]

31356-94-2
[Synonyms]

8-BR-CGMP
8-BROMO-CGMP
8-bromocyclic GMP
8-Bromoguanosine3&rsquo
8-bromo-3',5'-cyclic GMP
-cyclicmonophosphoricacid
8-Bromoguanosine 3',5'-phosphoric acid
8-BROMOGUANOSINE-3',5'-CYCLIC MONOPHOSPHATE
8-BROMOGUANOSINE-3',5'-CYCLIC-MONOPHOSPHORIC ACID
Guanosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate)
8-Bromoguanosine-3'',5''-cyclic monophosphoric acid sodium salt
2-amino-8-bromo-9-[(1S,6R,8R,9R)-3,9-dihydroxy-3-oxo-2,4,7-trioxa-3$l^{5}-phosphabicyclo[4.3.0]nonan-8-yl]-3H-purin-6-one
2-azanyl-8-bromo-9-[(1S,6R,8R,9R)-3,9-dihydroxy-3-oxo-2,4,7-trioxa-3$l^{5}-phosphabicyclo[4.3.0]nonan-8-yl]-3H-purin-6-one
2-amino-8-bromo-9-[(1S,6R,8R,9R)-3,9-dihydroxy-3-keto-2,4,7-trioxa-3$l^{5}-phosphabicyclo[4.3.0]nonan-8-yl]-3H-purin-6-one
[Molecular Formula]

C10H11BrN5O7P
[MDL Number]

MFCD00038423
[MOL File]

31356-94-2.mol
[Molecular Weight]

424.1
Chemical PropertiesBack Directory
[density ]

2.96±0.1 g/cm3(Predicted)
[pka]

1.01±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

8-Bromoguanosine 3'', 5'' -cyclic monophosphoric acid
[Definition]

ChEBI: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP bearing an additional bromo substituent at position 8 on the guanine ring. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activatin PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro.
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