| Identification | Back Directory | [Name]
HIPPURYL-HIS-LEU | [CAS]
31373-65-6 | [Synonyms]
Bz-Gly-His-Leu
HIPPURYL-HIS-LEU
H-HIP-HIS-LEU-OH
BZ-GLY-HIS-LEU-OH
HIPPURYL-HIS-LEU-OH
BENZOYL-GLY-HIS-LEU
HIPPURYL-HISTIDYL-LEUCINE
N-Benzoyl-Gly-L-His-L-Leu-OH
HIPPURYL-L-HISTIDYL-L-LEUCINE
Nα-(Benzoylglycyl)-L-His-L-Leu-OH
Hippuryl-His-Leu-OH |Bz-Gly-His-Leu-OH
N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine
Hippuryl-L-histidyl-L-leucine, tetrahydrate,99%
Hippuryl-L-histidyl-L-leucine, free base(Synthetic) | [EINECS(EC#)]
250-597-9 | [Molecular Formula]
C21H27N5O5 | [MDL Number]
MFCD00005205 | [MOL File]
31373-65-6.mol | [Molecular Weight]
429.47 |
| Chemical Properties | Back Directory | [Appearance]
white fine crystalline powder | [Boiling point ]
912.4±65.0 °C(Predicted) | [density ]
1.283±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
acetic acid: 50 mg/mL, clear, colorless
| [form ]
powder
| [pka]
3.26±0.10(Predicted) | [color ]
white to off-white
| [Sequence]
Hippuryl-His-Leu-OH |
| Hazard Information | Back Directory | [Chemical Properties]
white fine crystalline powder | [Uses]
Hippuryl-His-Leu-OH is a substrate for detecting the activity of angiotensin I converting enzyme. The His-Leu released by Hippuryl-His-Leu-OH can react with o-phtbaldialdehyde or Fluorescamine (HY-D0715) for fluorescence detection[1][2][3]. | [References]
[1] Nishimura K, et al. Purification of angiotensin I-converting enzyme from human lung. Biochim Biophys Acta. 1977 Aug 11;483(2):398-408. DOI:10.1016/0005-2744(77)90067-5
[2] Santos RA, et al. An improved fluorometric assay of rat serum and plasma converting enzyme. Hypertension. 1985 Mar-Apr;7(2):244-52. DOI:10.1161/01.hyp.7.2.244
[3] Horiuchi M, et al. Method for determination of angiotensin-converting enzyme activity in blood and tissue by high-performance liquid chromatography. J Chromatogr. 1982 Dec 10;233:123-30. DOI:10.1016/s0378-4347(00)81738-7 |
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